6MHG

Cryo-EM structure of the circumsporozoite protein of Plasmodium falciparum with a vaccine-elicited antibody reveals maturation of inter-antibody contacts

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (E)	circumsporozoite protein	polymer	278	30232.2	1	Pfam (PF00090) UniProt (by SIFTS) (Q7K740)	Plasmodium falciparum
2	B, D, F, H, J... (H, A, B, C, D...)	Fab311 heavy chain	polymer	225	24098.9	11	UniProt (V9HW68) Pfam (PF07686) Pfam (PF07654)	Homo sapiens (Human)
3	C, E, G, I, K... (L, N, O, P, Q...)	Fab311 light chain	polymer	218	22980.5	11		Homo sapiens (Human)

Sequence modifications

H, A, B, C, D, F, G, I, J, K, M: 1 - 102 (PDB: 6MHG)
H, A, B, C, D, F, G, I, J, K, M: 103 - 217 (UniProt: V9HW68)

Contents of the asymmetric unit

Polymers	Number of chains	23
	Total formula weight	548105.1
All*	Total formula weight	548105.1

*Water molecules are not included.