6MHF
Galphai3 co-crystallized with GIV/Girdin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Guanine nucleotide-binding protein G(k) subunit alpha | polymer | 350 | 40066.4 | 1 | UniProt (P08753) Pfam (PF00503) | Rattus norvegicus (Rat) | G(i) alpha-3 |
| 2 | B (C) | Girdin | polymer | 31 | 3312.7 | 1 | UniProt (Q3V6T2) | Homo sapiens | Akt phosphorylation enhancer,APE,Coiled-coil domain-containing protein 88A,G alpha-interacting vesicle-associated protein,GIV,Girders of actin filament,Hook-related protein 1,HkRP1 |
| 3 | C (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 26 - 354 (UniProt: P08753)
| PDB | External Database | Details |
|---|---|---|
| Met 5 | - | initiating methionine |
| Gly 6 | - | expression tag |
| Ser 7 | - | expression tag |
| Ser 8 | - | expression tag |
| His 9 | - | expression tag |
| His 10 | - | expression tag |
| His 11 | - | expression tag |
| His 12 | - | expression tag |
| His 13 | - | expression tag |
| His 14 | - | expression tag |
| Ser 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Val 19 | - | expression tag |
| Pro 20 | - | expression tag |
| Arg 21 | - | expression tag |
| Gly 22 | - | expression tag |
| Ser 23 | - | expression tag |
| His 24 | - | expression tag |
| Met 25 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 43379.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 535.3 | |
| All* | Total formula weight | 43914.4 |
