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6MHE

Galphai3 co-crystallized with KB752

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Guanine nucleotide-binding protein G(k) subunit alphapolymer35040066.41UniProt (P08753)
Pfam (PF00503)
Rattus norvegicus (Rat)G(i) alpha-3
2B
(C)
KB752 peptidepolymer162037.31synthetic construct
3C
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
4D
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
5E, F
(A, C)
waterwater18.077Chemie (HOH)
Sequence modifications
A: 26 - 354 (UniProt: P08753)
PDBExternal DatabaseDetails
Met 5-initiating methionine
Gly 6-expression tag
Ser 7-expression tag
Ser 8-expression tag
His 9-expression tag
His 10-expression tag
His 11-expression tag
His 12-expression tag
His 13-expression tag
His 14-expression tag
Ser 15-expression tag
Ser 16-expression tag
Gly 17-expression tag
Leu 18-expression tag
Val 19-expression tag
Pro 20-expression tag
Arg 21-expression tag
Gly 22-expression tag
Ser 23-expression tag
His 24-expression tag
Met 25-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight42103.7
Non-Polymers*Number of molecules2
Total formula weight535.3
All*Total formula weight42639.0
*Water molecules are not included.

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PDB entries from 2025-12-17

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