6MGR

Crystal Structure of the Catalytic Domain of the Inosine Monophosphate Dehydrogenase from Campylobacter jejuni in the complex with inhibitor Oxanosine monophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Inosine monophosphate dehydrogenase	polymer	385	41053.2	4	UniProt (A0A2R4D3F6)	Campylobacter jejuni	IMP dehydrogenase
2	E, IA, O, Z (A, D, B, C)	5-[(Z)-(aminomethylidene)amino]-1-(5-O-phosphono-beta-D-ribofuranosyl)-1H-imidazole-4-carboxylic acid	non-polymer		366.2	4	Chemie (JQS)
3	AA, CA, DA, EA, F... (C, A, D, B)	SULFATE ION	non-polymer		96.1	17	Chemie (SO4)
4	BA, H, I, J, K... (C, A, D, B)	CHLORIDE ION	non-polymer		35.5	10	Chemie (CL)
5	GA, L, X (C, A, B)	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	3	Chemie (MPD)
6	HA, M, N, U, Y (D, A, B, C)	POTASSIUM ION	non-polymer		39.1	5	Chemie (K)
7	RA, SA, TA, UA (A, B, C, D)	water	water		18.0	428	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 194 (UniProt: A0A2R4D3F6)

PDB	External Database	Details
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

A, B, C, D: 196 - 485 (UniProt: A0A2R4D3F6)

PDB	External Database	Details
Gly 195	-	linker

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164212.7
Non-Polymers*	Number of molecules	39
	Total formula weight	4002.5
All*	Total formula weight	168215.2

*Water molecules are not included.