6MGP

Structure of human 4-1BB / 4-1BBL complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Tumor necrosis factor ligand superfamily member 9	polymer	207	21937.8	3	UniProt (P41273) Pfam (PF00229)	Homo sapiens (Human)	4-1BB ligand,4-1BBL
2	D, E, F (X, Y, Z)	Tumor necrosis factor receptor superfamily member 9	polymer	144	15670.6	3	UniProt (Q07011) Pfam (PF00020)	Homo sapiens (Human)	4-1BB ligand receptor,CDw137,T-cell antigen 4-1BB homolog,T-cell antigen ILA
3	G, H, I (D, E, F)	alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		716.7	3	In PDB GlyTouCan (G63564LA)
4	J, K, N, O, P (A, C, X, Y)	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
5	L, M, Q, R (B, C, Z)	GLYCEROL	non-polymer		92.1	4	Chemie (GOL)
6	S, T, U, V, W... (A, B, C, X, Y...)	water	water		18.0	88	Chemie (HOH)

Sequence modifications

A, B, C: 58 - 254 (UniProt: P41273)

PDB	External Database	Details
Gly 255	-	expression tag
Ser 256	-	expression tag
His 257	-	expression tag
His 258	-	expression tag
His 259	-	expression tag
His 260	-	expression tag
His 261	-	expression tag
His 262	-	expression tag
His 263	-	expression tag
His 264	-	expression tag

X, Y, Z: 25 - 162 (UniProt: Q07011)

PDB	External Database	Details
Glu 163	-	expression tag
Asn 164	-	expression tag
Leu 165	-	expression tag
Tyr 166	-	expression tag
Phe 167	-	expression tag
Gln 168	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	112825.2
Branched	Number of molecules	3
	Total formula weight	2150.0
Non-Polymers*	Number of molecules	9
	Total formula weight	663.6
All*	Total formula weight	115638.9

*Water molecules are not included.