6MGG

Succinyl-CoA synthase from Francisella tularensis, phosphorylated, in complex with CoA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Succinate--CoA ligase [ADP-forming] subunit alpha	polymer	296	31029.6	2	UniProt (A0A0G2RQ73) Pfam (PF02629) Pfam (PF00549) UniProt (by SIFTS) (Q5NHF4)	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	Succinyl-CoA synthetase subunit alpha,SCS-alpha
2	B, D (B, D)	Succinate--CoA ligase [ADP-forming] subunit beta	polymer	387	41620.6	2	UniProt (Q5NHF3) Pfam (PF08442) Pfam (PF00549)	Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)	Succinyl-CoA synthetase subunit beta,SCS-beta
3	E, I (A, C)	COENZYME A	non-polymer		767.5	2	Chemie (COA)
4	F, J (A, C)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	G, H, K, L (B, D)	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6	M, N, O, P (A, B, C, D)	water	water		18.0	1076	Chemie (HOH)

Sequence modifications

A, C: 1 - 290 (UniProt: A0A0G2RQ73)

PDB	External Database	Details
Val 85	Ala 85	engineered mutation
Glu 291	-	expression tag
Asn 292	-	expression tag
Leu 293	-	expression tag
Tyr 294	-	expression tag
Phe 295	-	expression tag
Gln 296	-	expression tag

B, D: 1 - 387 (UniProt: Q5NHF3)

PDB	External Database	Details
Thr 69	Ala 69	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	145300.4
Non-Polymers*	Number of molecules	8
	Total formula weight	1831.9
All*	Total formula weight	147132.3

*Water molecules are not included.