6MFM

Structure of thiamine-monophosphate kinase from Acinetobacter baumannii in complex with adenosine diphosphate (ADP) and thiamine diphosphate (TPP), orthorhombic crystal form

Replaces:  5D9U

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thiamine-monophosphate kinase	polymer	313	34360.0	2	UniProt (A0A0D5YC82) Pfam (PF00586) Pfam (PF02769)	Acinetobacter baumannii	Thiamine-phosphate kinase
2	C, O (A, B)	THIAMINE DIPHOSPHATE	non-polymer		425.3	2	Chemie (TPP)
3	D, E, F, G, J... (A, B)	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)
4	H, L (A, B)	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	2	Chemie (ADP)
5	I, K, M, N (A, B)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
6	S, T (A, B)	water	water		18.0	452	Chemie (HOH)

Sequence modifications

A, B: 1 - 305 (UniProt: A0A0D5YC82)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	68720.0
Non-Polymers*	Number of molecules	16
	Total formula weight	1991.4
All*	Total formula weight	70711.4

*Water molecules are not included.