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6MEJ

Crystal structure of Hepatitis C virus envelope glycoprotein E2 ectodomain in complex with human antibodies HEPC3 and HEPC46

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
antibody HEPC46 Heavy Chainpolymer23024681.61Homo sapiens
2B
(B)
antibody HEPC46 Light Chainpolymer21722938.21Homo sapiens
3C
(C)
E2 glycoproteinpolymer26228769.51UniProt (C1KH25)
Pfam (PF01560)
Hepacivirus C
4D
(H)
antibody HEPC3 Heavy Chainpolymer24125759.81Homo sapiens
5E
(L)
antibody HEPC3 Light Chainpolymer21423384.91Homo sapiens
6F
(D)
alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched910.81In PDB
GlyTouCan (G32708SB)
7G
(E)
alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched748.71In PDB
GlyTouCan (G81315DD)
8H, I, J, K
(C)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.24Chemie (NAG)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight125534.0
BranchedNumber of molecules2
Total formula weight1659.5
Non-Polymers*Number of molecules4
Total formula weight884.8
All*Total formula weight128078.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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