6MEI
Crystal structure of broadly neutralizing antibody HEPC3 in complex with Hepatitis C virus envelope glycoprotein E2 ectodomain
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | E2 glycoprotein | polymer | 270 | 29945.6 | 1 | UniProt (A0A2P0NE26) Pfam (PF01560) In PDB | Hepacivirus C | |
2 | H | antibody HEPC3 Heavy Chain | polymer | 241 | 25759.8 | 1 | Homo sapiens | ||
3 | L | antibody HEPC3 Light Chain | polymer | 214 | 23384.9 | 1 | Homo sapiens | ||
4 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | B, D | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 2 | In PDB GlyTouCan (G15407YE) | |||
6 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 5 | Chemie (NAG) | |||
7 | C, H, L | BROMIDE ION | non-polymer | 79.9 | 7 | Chemie (BR) | |||
8 | water | water | 18.0 | 204 | Chemie (HOH) |
Sequence modifications
C: 384 - 645 (UniProt: A0A2P0NE26)
PDB | External Database | Details |
---|---|---|
Ile 646 | - | expression tag |
Gly 647 | - | expression tag |
His 648 | - | expression tag |
His 649 | - | expression tag |
His 650 | - | expression tag |
His 651 | - | expression tag |
His 652 | - | expression tag |
His 653 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 79090.2 | |
Branched | Number of molecules | 3 |
Total formula weight | 1597.5 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 1665.4 | |
All* | Total formula weight | 82353.1 |