6MCU
Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:T51D:A28H mutant of human Cellular Retinol Binding Protein II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Retinol-binding protein 2 | polymer | 133 | 15679.6 | 12 | UniProt (P50120) Pfam (PF00061) | Homo sapiens (Human) | Cellular retinol-binding protein II,CRBP-II |
| 2 | M, P, T (F, H, L) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 3 | N, O, Q, R, S (F, G, H, J, K) | RETINAL | non-polymer | 284.4 | 5 | Chemie (RET) | |||
| 4 | AA, BA, CA, DA, EA... (G, H, I, J, K...) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L: 1 - 133 (UniProt: P50120)
| PDB | External Database | Details |
|---|---|---|
| His 28 | Ala 29 | engineered mutation |
| Asp 51 | Thr 52 | engineered mutation |
| Lys 108 | Gln 109 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 188154.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1698.5 | |
| All* | Total formula weight | 189853.1 |
