6MCP

L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	LegK7	polymer	523	60684.2	2	UniProt (Q5ZU83) In PDB	Legionella pneumophila subsp. pneumophila
2	B, D	MOB kinase activator 1A	polymer	187	21669.7	2	UniProt (Q9H8S9) Pfam (PF03637) In PDB	Homo sapiens (Human)	Mob1 alpha, Mob1A, Mob1 homolog 1B, Mps one binder kinase activator-like 1B
3	A, D	TETRAETHYLENE GLYCOL	non-polymer		194.2	3	Chemie (PG4)
4	C, A, D, B	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	18	Chemie (PEG)
5	A, B, C	HEXAETHYLENE GLYCOL	non-polymer		282.3	4	Chemie (P6G)
6	D, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
7	C	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
8	C	PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER	non-polymer		506.2	1	Chemie (ANP)
9		water	water		18.0	109	Chemie (HOH)

Sequence modifications

A, C: 11 - 530 (UniProt: Q5ZU83)

PDB	External Database	Details
Ser 8	-	expression tag
Asn 9	-	expression tag
Ala 10	-	expression tag

B, D: 33 - 213 (UniProt: Q9H8S9)

PDB	External Database	Details
Ser 30	-	expression tag
Asn 31	-	expression tag
Ala 32	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	164707.8
Non-Polymers*	Number of molecules	29
	Total formula weight	4314.1
All*	Total formula weight	169022.0

*Water molecules are not included.