6MCP

L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue PG4 A 601

Chain	Residue
A	GLN262
A	ASN318
B	GLY73

---

site_id	AC2
Number of Residues	4
Details	binding site for residue PEG A 602

Chain	Residue
A	LYS28
A	PHE70
A	GLU92
A	PEG603

---

site_id	AC3
Number of Residues	3
Details	binding site for residue PEG A 603

Chain	Residue
A	PEG602
A	LYS28
A	GLU92

---

site_id	AC4
Number of Residues	3
Details	binding site for residue PEG A 604

Chain	Residue
A	ARG367
A	ASN368
A	HOH734

---

site_id	AC5
Number of Residues	5
Details	binding site for residue PEG A 605

Chain	Residue
A	LYS309
A	ASN311
A	SER342
A	PRO343
A	LEU344

---

site_id	AC6
Number of Residues	3
Details	binding site for residue P6G A 606

Chain	Residue
A	LYS163
A	ALA166
C	ASP274

---

site_id	AC7
Number of Residues	6
Details	binding site for residue P6G A 607

Chain	Residue
A	TYR107
A	ILE149
A	PHE231
A	GLU233
B	GLN172
B	GLN174

---

site_id	AC8
Number of Residues	2
Details	binding site for residue PEG A 608

Chain	Residue
A	VAL363
A	GLY364

---

site_id	AC9
Number of Residues	3
Details	binding site for residue PEG A 609

Chain	Residue
A	TYR365
A	ASN366
A	LEU370

---

site_id	AD1
Number of Residues	3
Details	binding site for residue PEG A 610

Chain	Residue
A	LYS37
A	GLU119
B	SER146

---

site_id	AD2
Number of Residues	5
Details	binding site for residue PG4 A 611

Chain	Residue
A	GLN115
A	LYS124
A	THR127
A	ARG128
A	THR442

---

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN B 301

Chain	Residue
B	CYS79
B	CYS84
B	HIS161
B	HIS166

---

site_id	AD4
Number of Residues	5
Details	binding site for residue P6G B 303

Chain	Residue
A	LYS372
B	MET145
B	LYS149
B	PHE193
B	ASN194

---

site_id	AD5
Number of Residues	8
Details	binding site for residue PEG B 304

Chain	Residue
B	GLU55
B	PRO133
B	SER134
B	LYS135
B	ILE136
B	VAL138
B	PRO139
B	PHE140

---

site_id	AD6
Number of Residues	3
Details	binding site for residue MN C 601

Chain	Residue
C	ASN312
C	ASP324
C	ANP610

---

site_id	AD7
Number of Residues	6
Details	binding site for residue P6G C 602

Chain	Residue
C	ASN105
C	ILE106
C	TYR107
C	LYS145
C	GLU233
D	GLN174

---

site_id	AD8
Number of Residues	2
Details	binding site for residue PEG C 603

Chain	Residue
C	ARG367
C	ASN368

---

site_id	AD9
Number of Residues	3
Details	binding site for residue PEG C 604

Chain	Residue
C	ASN261
C	GLN262
D	GLY73

---

site_id	AE1
Number of Residues	5
Details	binding site for residue PEG C 605

Chain	Residue
C	LYS124
C	THR127
C	ARG128
C	THR442
C	HOH706

---

site_id	AE2
Number of Residues	4
Details	binding site for residue PEG C 606

Chain	Residue
C	ARG152
C	GLU233
D	PHE78
D	LEU173

---

site_id	AE3
Number of Residues	2
Details	binding site for residue PEG C 607

Chain	Residue
C	LYS28
C	LYS69

---

site_id	AE4
Number of Residues	2
Details	binding site for residue PEG C 608

Chain	Residue
C	PRO362
C	GLY364

---

site_id	AE5
Number of Residues	1
Details	binding site for residue PEG C 609

Chain	Residue
C	TYR365

---

site_id	AE6
Number of Residues	13
Details	binding site for residue ANP C 610

Chain	Residue
A	PHE195
C	ASN192
C	ASN194
C	GLN258
C	PHE259
C	ALA260
C	ASN263
C	ASN264
C	ASN311
C	ASN312
C	LEU314
C	ASP324
C	MN601

---

site_id	AE7
Number of Residues	4
Details	binding site for residue ZN D 301

Chain	Residue
D	CYS84
D	HIS161
D	HIS166
D	CYS79

---

site_id	AE8
Number of Residues	2
Details	binding site for residue PG4 D 302

Chain	Residue
D	MET145
D	LYS149

---

site_id	AE9
Number of Residues	3
Details	binding site for residue PEG D 303

Chain	Residue
D	TYR163
D	HIS164
D	PHE167

---

site_id	AF1
Number of Residues	3
Details	binding site for residue PEG D 304

Chain	Residue
C	ARG420
D	GLU55
D	LYS135

---

Functional Information from PROSITE/UniProt

site_id	PS00061
Number of Residues	29
Details	ADH_SHORT Short-chain dehydrogenases/reductases family signature. DrhelgkeqeLhsYGVSKYFIeDYSvFMM

Chain	Residue	Details
A	ASP212-MET240

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12962634","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18328708","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine; by STK3/MST2","evidences":[{"source":"PubMed","id":"18362890","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18362890","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---