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6MC9

Crystal Structure of Human Nav1.4 C-Terminal (1599-1754) domain in complex with calcium-bound calmodulin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Sodium channel protein type 4 subunit alphapolymer16819211.91UniProt (P35499)Homo sapiens (Human)SkM1,Sodium channel protein skeletal muscle subunit alpha,Sodium channel protein type IV subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.4
2B
(B)
Calmodulin-1polymer14916852.51UniProt (P0DP29)
Pfam (PF13499)
Rattus norvegicus (Rat)
3C, D, E, F
(B)
CALCIUM IONnon-polymer40.14Chemie (CA)
Sequence modifications
A: 1599 - 1754 (UniProt: P35499)
PDBExternal DatabaseDetails
Gly 1594-expression tag
Pro 1595-expression tag
Leu 1596-expression tag
Gly 1597-expression tag
Ser 1598-expression tag
Leu 1755-expression tag
Thr 1756-expression tag
Arg 1757-expression tag
Ala 1758-expression tag
Ala 1759-expression tag
Ala 1760-expression tag
Ser 1761-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight36064.5
Non-Polymers*Number of molecules4
Total formula weight160.3
All*Total formula weight36224.8
*Water molecules are not included.

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PDB entries from 2024-10-30

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