6MC9
Crystal Structure of Human Nav1.4 C-Terminal (1599-1754) domain in complex with calcium-bound calmodulin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | Sodium channel protein type 4 subunit alpha | polymer | 168 | 19211.9 | 1 | UniProt (P35499) | Homo sapiens (Human) | SkM1,Sodium channel protein skeletal muscle subunit alpha,Sodium channel protein type IV subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.4 |
2 | B (B) | Calmodulin-1 | polymer | 149 | 16852.5 | 1 | UniProt (P0DP29) Pfam (PF13499) | Rattus norvegicus (Rat) | |
3 | C, D, E, F (B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
A: 1599 - 1754 (UniProt: P35499)
PDB | External Database | Details |
---|---|---|
Gly 1594 | - | expression tag |
Pro 1595 | - | expression tag |
Leu 1596 | - | expression tag |
Gly 1597 | - | expression tag |
Ser 1598 | - | expression tag |
Leu 1755 | - | expression tag |
Thr 1756 | - | expression tag |
Arg 1757 | - | expression tag |
Ala 1758 | - | expression tag |
Ala 1759 | - | expression tag |
Ala 1760 | - | expression tag |
Ser 1761 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36064.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 160.3 | |
All* | Total formula weight | 36224.8 |