6MBK
SETD3, a Histidine Methyltransferase, in Complex with an Actin Peptide and SAH, First P212121 Crystal Form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (Y, Z) | Actin peptide | polymer | 15 | 1788.0 | 2 | UniProt (P60709) | Homo sapiens | Beta-actin |
| 2 | B, D (A, B) | Histone-lysine N-methyltransferase setd3 | polymer | 599 | 67753.5 | 2 | UniProt (Q86TU7) Pfam (PF00856) Pfam (PF09273) | Homo sapiens (Human) | SET domain-containing protein 3 |
| 3 | E, P (A, B) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 2 | Chemie (SAH) | |||
| 4 | F, G, H, I, J... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 14 | Chemie (EDO) | |||
| 5 | L, M, Y, Z (A, B) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | AA, BA, N, O (B, A) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 7 | CA, DA, EA, FA (Y, A, Z, B) | water | water | 18.0 | 833 | Chemie (HOH) |
Sequence modifications
A, B: 0 - 593 (UniProt: Q86TU7)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Leu -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 139083.0 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 2390.4 | |
| All* | Total formula weight | 141473.4 |
