6MBA
Crystal Structure of Human Nav1.4 CTerminal Domain in Complex with apo Calmodulin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sodium channel protein type 4 subunit alpha | polymer | 171 | 19607.2 | 1 | UniProt (P35499) | Homo sapiens (Human) | SkM1,Sodium channel protein skeletal muscle subunit alpha,Sodium channel protein type IV subunit alpha,Voltage-gated sodium channel subunit alpha Nav1.4 |
| 2 | B (B) | Calmodulin-1 | polymer | 149 | 16852.5 | 1 | UniProt (P0DP29) Pfam (PF13499) | Rattus norvegicus (Rat) | |
| 3 | C, D, E, F (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | G (B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | H (B) | CARBONATE ION | non-polymer | 60.0 | 1 | Chemie (CO3) | |||
| 6 | I (B) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 7 | J, K (A, B) | water | water | 18.0 | 120 | Chemie (HOH) |
Sequence modifications
A: 1599 - 1764 (UniProt: P35499)
| PDB | External Database | Details |
|---|---|---|
| Gly 1594 | - | expression tag |
| Pro 1595 | - | expression tag |
| Leu 1596 | - | expression tag |
| Gly 1597 | - | expression tag |
| Ser 1598 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36459.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 386.0 | |
| All* | Total formula weight | 36845.8 |
