6MAO

Crystal structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase from Legionella pneumophila Philadelphia 1 in complex with dUMP (Deoxyuridine 5'-monophosphate)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Deoxyuridine 5'-triphosphate nucleotidohydrolase	polymer	160	17391.8	1	UniProt (Q5ZSN0) Pfam (PF00692) In PDB	Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)	dUTPase,dUTP pyrophosphatase
2	A	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	1	Chemie (UMP)
3	A	(4S)-2-METHYL-2,4-PENTANEDIOL	non-polymer		118.2	1	Chemie (MPD)
4	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
5		water	water		18.0	134	Chemie (HOH)

Sequence modifications

A: 1 - 152 (UniProt: Q5ZSN0)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17391.8
Non-Polymers*	Number of molecules	3
	Total formula weight	522.4
All*	Total formula weight	17914.2

*Water molecules are not included.