6MAO

Crystal structure of Deoxyuridine 5'-triphosphate nucleotidohydrolase from Legionella pneumophila Philadelphia 1 in complex with dUMP (Deoxyuridine 5'-monophosphate)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004170	molecular_function	dUTP diphosphatase activity
A	0006226	biological_process	dUMP biosynthetic process
A	0009117	biological_process	nucleotide metabolic process
A	0016787	molecular_function	hydrolase activity
A	0046081	biological_process	dUTP catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue UMP A 201

Chain	Residue
A	SER72
A	HOH301
A	HOH315
A	HOH327
A	HOH352
A	HOH382
A	ASN84
A	GLY87
A	LEU88
A	ILE89
A	ASP90
A	TYR93
A	LYS98
A	MPD202

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site_id	AC2
Number of Residues	3
Details	binding site for residue MPD A 202

Chain	Residue
A	SER72
A	LYS77
A	UMP201

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site_id	AC3
Number of Residues	3
Details	binding site for residue SO4 A 203

Chain	Residue
A	ARG34
A	ARG116
A	HOH311

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00116

Chain	Residue	Details
A	ARG71
A	ASN84
A	LEU88
A	LYS98

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