6MA1
Crystal structure of human O-GlcNAc transferase bound to a peptide from HCF-1 pro-repeat 2 (11-26) and inhibitor 4a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | polymer | 723 | 80974.5 | 1 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | Homo sapiens (Human) | O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,OGT |
| 2 | B (B) | Host Cell Factor 1 peptide | polymer | 16 | 1608.6 | 1 | UniProt (by SIFTS) (P51610) | Homo sapiens | |
| 3 | C (A) | N-[(2R)-2-{[(7-chloro-2-oxo-1,2-dihydroquinolin-6-yl)sulfonyl]amino}-2-(2-methoxyphenyl)acetyl]-N-[(thiophen-2-yl)methyl]glycine | non-polymer | 576.0 | 1 | Chemie (JA4) | |||
| 4 | D (A) | water | water | 18.0 | 41 | Chemie (HOH) |
Sequence modifications
A: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 82583.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 576.0 | |
| All* | Total formula weight | 83159.1 |
