6M7X
Structure of human CYP11B1 in complex with fadrozole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Cytochrome P450 11B1, mitochondrial | polymer | 484 | 55676.3 | 2 | UniProt (P15538) Pfam (PF00067) In PDB | Homo sapiens (Human) | CYPXIB1,Cytochrome P-450c11,Cytochrome P450C11,Steroid 11-beta-hydroxylase |
| 2 | A, B | 4-[(5S)-5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl]benzonitrile | non-polymer | 223.3 | 2 | Chemie (JD7) | |||
| 3 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 4 | water | water | 18.0 | 428 | Chemie (HOH) |
Sequence modifications
A, B: 31 - 503 (UniProt: P15538)
| PDB | External Database | Details |
|---|---|---|
| Met 24 | - | expression tag |
| Ala 25 | - | expression tag |
| Lys 26 | - | expression tag |
| Lys 27 | - | expression tag |
| Thr 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Ser 30 | - | expression tag |
| His 504 | - | expression tag |
| His 505 | - | expression tag |
| His 506 | - | expression tag |
| His 507 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111352.7 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1679.5 | |
| All* | Total formula weight | 113032.2 |
