6M71

SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA-directed RNA polymerase	polymer	942	108162.5	1	UniProt (P0DTD1) Pfam (PF06478) Pfam (PF00680) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein,Pol,RdRp,Non-structural protein 12,nsp12,SARS-Cov-2 NSP 12
2	C	Non-structural protein 7	polymer	83	9248.8	1	UniProt (P0DTD1) Pfam (PF08716) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein,nsp7,SARS-Cov-2 NSP 7
3	D, B	Non-structural protein 8	polymer	198	21903.0	2	UniProt (P0DTD1) Pfam (PF08717) In PDB	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)	pp1ab,ORF1ab polyprotein,nsp8,SARS-Cov-2 NSP 8

Sequence modifications

A: 1 - 932 (UniProt: P0DTD1)

PDB	External Database	Details
His 933	-	expression tag
His 934	-	expression tag
His 935	-	expression tag
His 936	-	expression tag
His 937	-	expression tag
His 938	-	expression tag
His 939	-	expression tag
His 940	-	expression tag
His 941	-	expression tag
His 942	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	161217.4
All*	Total formula weight	161217.4

*Water molecules are not included.