6M69

Crystal structure of Mycobacterium smegmatis MutT1 in complex with GMPPCP (GDP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hydrolase, NUDIX family protein	polymer	342	38153.1	1	UniProt (A0QUZ2) Pfam (PF00293) Pfam (PF00300)	Mycolicibacterium smegmatis MC2 155
2	B (A)	GUANOSINE-5'-DIPHOSPHATE	non-polymer		443.2	1	Chemie (GDP) PubChem (136073927) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) PubChem (172898537)
3	C (A)	PYROPHOSPHATE 2-	non-polymer		176.0	1	Chemie (POP) PubChem (4995)
4	D, E (A)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	F (A)	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG) PubChem (888)
6	G (A)	water	water		18.0	371	Chemie (HOH)

Sequence modifications

A: 1 - 322 (UniProt: A0QUZ2)

PDB	External Database	Details
Met -19	-	expression tag
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	38153.1
Non-Polymers*	Number of molecules	5
	Total formula weight	767.6
All*	Total formula weight	38920.7

*Water molecules are not included.