6M2B
Crystal structure of human dihydroorotate dehydrogenase (DHODH) with S416
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Dihydroorotate dehydrogenase (quinone), mitochondrial | polymer | 390 | 42636.4 | 1 | UniProt (Q02127) Pfam (PF01180) In PDB | Homo sapiens (Human) | DHOdehase,Dihydroorotate oxidase |
2 | A | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 1 | Chemie (FMN) | |||
3 | A | OROTIC ACID | non-polymer | 156.1 | 1 | Chemie (ORO) | |||
4 | A | 2-[(E)-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]-methyl-hydrazinylidene]methyl]benzoic acid | non-polymer | 371.8 | 1 | Chemie (EZO) | |||
5 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A: 30 - 396 (UniProt: Q02127)
PDB | External Database | Details |
---|---|---|
Met 7 | - | expression tag |
Gly 8 | - | expression tag |
His 9 | - | expression tag |
His 10 | - | expression tag |
His 11 | - | expression tag |
His 12 | - | expression tag |
His 13 | - | expression tag |
His 14 | - | expression tag |
His 15 | - | expression tag |
His 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
Ser 19 | - | expression tag |
Ser 20 | - | expression tag |
Gly 21 | - | expression tag |
His 22 | - | expression tag |
Ile 23 | - | expression tag |
Asp 24 | - | expression tag |
Asp 25 | - | expression tag |
Asp 26 | - | expression tag |
Asp 27 | - | expression tag |
Lys 28 | - | expression tag |
His 29 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 42636.4 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 984.3 | |
All* | Total formula weight | 43620.7 |