6M1U

Crystal structure of the vertebrate conserved region (VCR) of human METTL16

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA N6-adenosine-methyltransferase METTL16,RNA N6-adenosine-methyltransferase METTL16	polymer	164	19179.5	1	UniProt (Q86W50)	Homo sapiens (Human)	Methyltransferase 10 domain-containing protein,Methyltransferase-like protein 16,N6-adenosine-methyltransferase METTL16,U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase,Methyltransferase 10 domain-containing protein,Methyltransferase-like protein 16,N6-adenosine-methyltransferase METTL16,U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase

Sequence modifications

A: 310 - 508 (UniProt: Q86W50)

PDB	External Database	Details
Met 309	-	initiating methionine

A: 509 - 562 (UniProt: Q86W50)

PDB	External Database	Details
Leu 563	-	expression tag
Glu 564	-	expression tag
His 565	-	expression tag
His 566	-	expression tag
His 567	-	expression tag
His 568	-	expression tag
His 569	-	expression tag
His 570	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	19179.5
All*	Total formula weight	19179.5

*Water molecules are not included.