6M08
Crystal structure of Lp-PLA2 in complex with a novel covalent inhibitor.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Platelet-activating factor acetylhydrolase | polymer | 371 | 42267.1 | 2 | UniProt (Q13093) Pfam (PF03403) In PDB | Homo sapiens (Human) | PAF acetylhydrolase,1-alkyl-2-acetylglycerophosphocholine esterase,2-acetyl-1-alkylglycerophosphocholine esterase,Group-VIIA phospholipase A2,gVIIA-PLA2,LDL-associated phospholipase A2,LDL-PLA(2),PAF 2-acylhydrolase |
2 | B | (2S)-2-[(Z)-3-[2-(diethylamino)ethyl-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]amino]-1-oxidanyl-3-oxidanylidene-prop-1-enyl]pyrrolidine-1-carboxylic acid | non-polymer | 533.6 | 1 | Chemie (BWL) | |||
3 | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 84534.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 533.6 | |
All* | Total formula weight | 85067.7 |