6M06
Crystal structure of Lp-PLA2 in complex with a novel covalent inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Platelet-activating factor acetylhydrolase | polymer | 371 | 42267.1 | 2 | UniProt (Q13093) Pfam (PF03403) | Homo sapiens (Human) | PAF acetylhydrolase,1-alkyl-2-acetylglycerophosphocholine esterase,2-acetyl-1-alkylglycerophosphocholine esterase,Group-VIIA phospholipase A2,gVIIA-PLA2,LDL-associated phospholipase A2,LDL-PLA(2),PAF 2-acylhydrolase |
| 2 | C, D (A, B) | (2S)-2-[(Z)-1,3-bis(oxidanyl)-3-oxidanylidene-prop-1-enyl]pyrrolidine-1-carboxylic acid | non-polymer | 201.2 | 2 | Chemie (BWF) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 172 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 84534.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 402.4 | |
| All* | Total formula weight | 84936.5 |
