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6LZL

Crystal structure of human dihydroorotate dehydrogenase (DHODH) with Piperine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Dihydroorotate dehydrogenase (quinone), mitochondrialpolymer36539654.31UniProt (Q02127)
Pfam (PF01180)
Homo sapiens (Human)DHOdehase,Dihydroorotate oxidase
2B
(A)
OROTIC ACIDnon-polymer156.11Chemie (ORO)
3C
(A)
FLAVIN MONONUCLEOTIDEnon-polymer456.31Chemie (FMN)
4D
(A)
(2E,4E)-5-(2H-1,3-benzodioxol-5-yl)-1-(piperidin-1-yl)penta-2,4-dien-1-onenon-polymer285.31Chemie (AYR)
5E
(A)
waterwater18.099Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight39654.3
Non-Polymers*Number of molecules3
Total formula weight897.8
All*Total formula weight40552.0
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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