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6LY7

PylRS C-terminus domain mutant bound with 1-Formyl-L-tryptophan and AMPNP

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Pyrrolysine--tRNA ligasepolymer27731999.61UniProt (A0A0F8JXW8)
Pfam (PF01409)
UniProt (by SIFTS) (Q8PWY1)
Methanosarcina mazeiPyrrolysyl-tRNA synthetase,PylRS
2B
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
3C, D
(A)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
4E
(A)
N1-FORMYL-TRYPTOPHANnon-polymer232.21Chemie (TRF)
5F
(A)
waterwater18.0153Chemie (HOH)
Sequence modifications
A: 185 - 454 (UniProt: A0A0F8JXW8)
PDBExternal DatabaseDetails
Met 178-expression tag
His 179-expression tag
His 180-expression tag
His 181-expression tag
His 182-expression tag
His 183-expression tag
His 184-expression tag
Gly 346Asn 346engineered mutation
Gln 348Cys 348engineered mutation
Gly 401Val 401engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31999.6
Non-Polymers*Number of molecules4
Total formula weight787.0
All*Total formula weight32786.6
*Water molecules are not included.

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PDB entries from 2024-11-13

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