6LWR

Crystal structure of human NEIL1(K242) bound to duplex DNA containing a cleaved C:T mismatch

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	Endonuclease 8-like 1	polymer	295	33301.2	2	UniProt (Q96FI4) Pfam (PF01149) Pfam (PF09292)	Homo sapiens (Human)	DNA glycosylase/AP lyase Neil1,DNA-(apurinic or apyrimidinic site) lyase Neil1,Endonuclease VIII-like 1,FPG1,Nei homolog 1,NEH1,Nei-like protein 1
2	B, F (B, F)	DNA (5'-D(*CP*GP*TP*CP*CP*(PDA))-3')	polymer	6	1849.2	2		Escherichia coli
3	C, G (C, G)	DNA (5'-D(*CP*GP*TP*CP*CP*(PDA))-3')	polymer	6	1784.2	2		Escherichia coli
4	D, H (D, H)	DNA (5'-D(*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*G)-3')	polymer	13	4016.6	2		Escherichia coli
5	I, J, K (A, B, E)	water	water		18.0	40	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	81902.4
All*	Total formula weight	81902.4

*Water molecules are not included.