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6LW5

Crystal structure of the human formyl peptide receptor 2 in complex with WKYMVm

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Soluble cytochrome b562,N-formyl peptide receptor 2polymer42747694.01UniProt (P0ABE7)
UniProt (P25090)
Pfam (PF07361)
Pfam (PF00001)
Escherichia coliCytochrome b-562,FMLP-related receptor I,FMLP-R-I,Formyl peptide receptor-like 1,HM63,Lipoxin A4 receptor,LXA4 receptor,RFP
2B
(B)
TRP-LYS-TYR-MET-VAL-QXVpolymer6857.11synthetic construct
3C, D
(A)
CHOLESTEROLnon-polymer386.72Chemie (CLR)
4E
(A)
waterwater18.01Chemie (HOH)
Sequence modifications
A: 1001 - 1106 (UniProt: P0ABE7)
PDBExternal DatabaseDetails
Pro 1000-expression tag
Trp 1007Met 29engineered mutation
Ile 1102His 124engineered mutation
Leu 1106Arg 128engineered mutation
A: 3 - 322 (UniProt: P25090)
PDBExternal DatabaseDetails
Leu 211Ser 211engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight48551.1
Non-Polymers*Number of molecules2
Total formula weight773.3
All*Total formula weight49324.4
*Water molecules are not included.

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PDB entries from 2024-11-06

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