6LVL
Crystal structure of FGFR2 in complex with 1,3,5-triazine derivative
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Fibroblast growth factor receptor 2 | polymer | 313 | 35806.2 | 2 | UniProt (P21802) Pfam (PF07714) In PDB | Homo sapiens (Human) | FGFR-2,K-sam,KGFR,Keratinocyte growth factor receptor |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 3 | A, B | N-ethyl-2-[[4-[[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl]amino]-1,3,5-triazin-2-yl]amino]benzenesulfonamide | non-polymer | 581.7 | 2 | Chemie (EVL) |
Sequence modifications
A, B: 459 - 768 (UniProt: P21802)
| PDB | External Database | Details |
|---|---|---|
| Gly 456 | - | expression tag |
| Ser 457 | - | expression tag |
| His 458 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71612.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1547.7 | |
| All* | Total formula weight | 73160.2 |
