6LSE
Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Genome polyprotein | polymer | 468 | 53408.5 | 1 | UniProt (E5RPG3) Pfam (PF00680) In PDB | Human enterovirus 71 (EV71) | |
2 | B | RNA (35-MER) | polymer | 35 | 11260.7 | 1 | synthetic construct | ||
3 | C | RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*CP*U)-3') | polymer | 19 | 6117.7 | 1 | synthetic construct | ||
4 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
5 | A | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
6 | C | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
7 | water | water | 18.0 | 171 | Chemie (HOH) |
Sequence modifications
A: 1 - 462 (UniProt: E5RPG3)
PDB | External Database | Details |
---|---|---|
Met 291 | Cys 2022 | engineered mutation |
His 463 | - | expression tag |
His 464 | - | expression tag |
His 465 | - | expression tag |
His 466 | - | expression tag |
His 467 | - | expression tag |
His 468 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 70786.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 433.5 | |
All* | Total formula weight | 71220.4 |