6LRT

Crystal structure of isocitrate lyase (Caur_3889) from Chloroflexus aurantiacus in complex with isocitrate and manganese ion

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, D, G, J, M...)	Isocitrate lyase	polymer	436	48286.1	8	UniProt (A9WDE7) Pfam (PF00463)	Chloroflexus aurantiacus (strain ATCC 29366 / DSM 635 / J-10-fl)
2	BA, GA, I, L, O... (S, V, A, D, G...)	ISOCITRIC ACID	non-polymer		192.1	8	Chemie (ICT)
3	CA, DA, EA, HA, IA... (S, V, A, D, G...)	GLYCEROL	non-polymer		92.1	12	Chemie (GOL)
4	AA, FA, JA, K, N... (P, S, V, A, D...)	MANGANESE (II) ION	non-polymer		54.9	8	Chemie (MN)
5	KA, LA, MA, NA, OA... (A, D, G, J, M...)	water	water		18.0	667	Chemie (HOH)

Sequence modifications

A, D, G, J, M, P, S, V: 1 - 424 (UniProt: A9WDE7)

PDB	External Database	Details
Met -11	-	initiating methionine
Arg -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	386289.0
Non-Polymers*	Number of molecules	28
	Total formula weight	3081.6
All*	Total formula weight	389370.7

*Water molecules are not included.