6LPT
Crystal structure of human D-2-hydroxyglutarate dehydrogenase in complex with D-lactate (D-LAC)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | D-2-hydroxyglutarate dehydrogenase, mitochondrial | polymer | 481 | 52332.9 | 2 | UniProt (Q8N465) Pfam (PF01565) Pfam (PF02913) | Homo sapiens (Human) | |
| 2 | C, F (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | LACTIC ACID | non-polymer | 90.1 | 2 | Chemie (LAC) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 206 | Chemie (HOH) |
Sequence modifications
A, B: 51 - 521 (UniProt: Q8N465)
| PDB | External Database | Details |
|---|---|---|
| Gly 47 | - | expression tag |
| Pro 48 | - | expression tag |
| Gly 49 | - | expression tag |
| Ser 50 | - | expression tag |
| His 522 | - | expression tag |
| His 523 | - | expression tag |
| His 524 | - | expression tag |
| His 525 | - | expression tag |
| His 526 | - | expression tag |
| His 527 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 104665.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1882.1 | |
| All* | Total formula weight | 106547.8 |
