6LPJ
A2AR crystallized in EROCOC17+4, LCP-SFX at 277 K
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Adenosine receptor A2a,Soluble cytochrome b562,Adenosine receptor A2a | polymer | 447 | 49974.3 | 1 | UniProt (P29274) UniProt (P0ABE7) Pfam (PF00001) Pfam (PF07361) In PDB | Homo sapiens (Human) | Cytochrome b-562 |
2 | A | 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol | non-polymer | 337.3 | 1 | Chemie (ZMA) | |||
3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | A | CHOLESTEROL | non-polymer | 386.7 | 3 | Chemie (CLR) | |||
5 | A | DODECANE | non-polymer | 170.3 | 1 | Chemie (D12) | |||
6 | A | PENTADECANE | non-polymer | 212.4 | 6 | Chemie (MYS) | |||
7 | A | HEXANE | non-polymer | 86.2 | 1 | Chemie (HEX) | |||
8 | A | Octadecane | non-polymer | 254.5 | 3 | Chemie (8K6) | |||
9 | A | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
10 | A | N-OCTANE | non-polymer | 114.2 | 3 | Chemie (OCT) | |||
11 | A | UNDECANE | non-polymer | 156.3 | 1 | Chemie (UND) | |||
12 | A | [(2~{R},3~{S})-2,3,4-tris(oxidanyl)butyl] (5~{R},9~{R},13~{R})-5,9,13,17-tetramethyloctadecanoate | non-polymer | 444.7 | 2 | Chemie (ER0) | |||
13 | A | TRIDECANE | non-polymer | 184.4 | 4 | Chemie (TRD) | |||
14 | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 2 - 208 (UniProt: P29274)
A: 1002 - 1106 (UniProt: P0ABE7)
A: 219 - 316 (UniProt: P29274)
PDB | External Database | Details |
---|---|---|
Met -24 | - | initiating methionine |
Lys -23 | - | expression tag |
Thr -22 | - | expression tag |
Ile -21 | - | expression tag |
Ile -20 | - | expression tag |
Ala -19 | - | expression tag |
Leu -18 | - | expression tag |
Ser -17 | - | expression tag |
Tyr -16 | - | expression tag |
Ile -15 | - | expression tag |
Phe -14 | - | expression tag |
Cys -13 | - | expression tag |
Leu -12 | - | expression tag |
Val -11 | - | expression tag |
Phe -10 | - | expression tag |
Ala -9 | - | expression tag |
Asp -8 | - | expression tag |
Tyr -7 | - | expression tag |
Lys -6 | - | expression tag |
Asp -5 | - | expression tag |
Asp -4 | - | expression tag |
Asp -3 | - | expression tag |
Asp -2 | - | expression tag |
Gly -1 | - | expression tag |
Ala 0 | - | expression tag |
Pro 1 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Trp 1007 | Met 29 | engineered mutation |
Ile 1102 | His 124 | engineered mutation |
Leu 1106 | Arg 128 | engineered mutation |
PDB | External Database | Details |
---|---|---|
His 317 | - | expression tag |
His 318 | - | expression tag |
His 319 | - | expression tag |
His 320 | - | expression tag |
His 321 | - | expression tag |
His 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
His 325 | - | expression tag |
His 326 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 49974.3 | |
Non-Polymers* | Number of molecules | 27 |
Total formula weight | 6082.9 | |
All* | Total formula weight | 56057.1 |