6LPF
The crystal structure of human cytoplasmic LRS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Leucine--tRNA ligase, cytoplasmic | polymer | 1092 | 125188.7 | 2 | UniProt (Q9P2J5) Pfam (PF00133) Pfam (PF08264) In PDB | Homo sapiens (Human) | Leucyl-tRNA synthetase,LeuRS |
2 | A, B | 5'-O-(L-leucylsulfamoyl)adenosine | non-polymer | 459.5 | 2 | Chemie (LSS) | |||
3 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | B | 2'-(L-NORVALYL)AMINO-2'-DEOXYADENOSINE | non-polymer | 365.4 | 1 | Chemie (VRT) | |||
5 | water | water | 18.0 | 682 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 1070 (UniProt: Q9P2J5)
PDB | External Database | Details |
---|---|---|
Met -21 | - | expression tag |
Gly -20 | - | expression tag |
His -19 | - | expression tag |
His -18 | - | expression tag |
His -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
His -10 | - | expression tag |
Ser -9 | - | expression tag |
Ser -8 | - | expression tag |
Gly -7 | - | expression tag |
His -6 | - | expression tag |
Ile -5 | - | expression tag |
Glu -4 | - | expression tag |
Gly -3 | - | expression tag |
Arg -2 | - | expression tag |
His -1 | - | expression tag |
Met 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 250377.5 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 1376.4 | |
All* | Total formula weight | 251753.9 |