6LLC
Discovery of A Dual Inhibitor of NQO1 and GSTP1 for Treating Malignant Glioblastoma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | NAD(P)H dehydrogenase [quinone] 1 | polymer | 273 | 30776.4 | 12 | UniProt (P15559) Pfam (PF02525) | Homo sapiens (Human) | Azoreductase,DT-diaphorase,DTD,Menadione reductase,NAD(P)H:quinone oxidoreductase 1,Phylloquinone reductase,Quinone reductase 1,QR1 |
| 2 | BA, CA, FA, HA, JA... (H, I, J, K, L...) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 12 | Chemie (FAD) | |||
| 3 | AA, DA, EA, IA, N... (H, I, J, L, A...) | 5-methyl-N-(5-nitro-1,3-thiazol-2-yl)-3-phenyl-1,2-oxazole-4-carboxamide | non-polymer | 330.3 | 8 | Chemie (EHL) | |||
| 4 | GA, O, U, Y (J, A, D, F) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | KA, LA, MA, NA, OA... (A, B, C, D, E...) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 369316.9 | |
| Non-Polymers* | Number of molecules | 24 |
| Total formula weight | 12453.4 | |
| All* | Total formula weight | 381770.3 |
