6LKW
Structural and functional insights into macrophage migration inhibitory factor from Oncomelania hupensis, the intermediate host of Schistosoma japonicum
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Macrophage migration inhibitory factor | polymer | 138 | 15639.2 | 1 | UniProt (A0A1U9W5E8) Pfam (PF01187) | Oncomelania hupensis | |
| 2 | B (B) | Macrophage migration inhibitory factor | polymer | 139 | 15710.3 | 1 | UniProt (A0A1U9W5E8) Pfam (PF01187) | Oncomelania hupensis | |
| 3 | C (D) | Macrophage migration inhibitory factor | polymer | 137 | 15299.8 | 1 | UniProt (A0A1U9W5E8) Pfam (PF01187) | Oncomelania hupensis | |
| 4 | D (C) | Macrophage migration inhibitory factor | polymer | 134 | 15026.5 | 1 | UniProt (A0A1U9W5E8) Pfam (PF01187) | Oncomelania hupensis | |
| 5 | E, F (A, B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 6 | G, H, I, J (A, B, D, C) | water | water | 18.0 | 114 | Chemie (HOH) |
Sequence modifications
A: 1 - 131 (UniProt: A0A1U9W5E8)
B: 1 - 131 (UniProt: A0A1U9W5E8)
D: 1 - 131 (UniProt: A0A1U9W5E8)
C: 2 - 131 (UniProt: A0A1U9W5E8)
| PDB | External Database | Details |
|---|---|---|
| Asn 89 | Lys 89 | See sequence details |
| Val 90 | Ile 90 | See sequence details |
| Ile 125 | Asn 125 | See sequence details |
| Tyr 132 | - | expression tag |
| Leu 133 | - | expression tag |
| His 134 | - | expression tag |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| His 137 | - | expression tag |
| His 138 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asn 89 | Lys 89 | See sequence details |
| Val 90 | Ile 90 | See sequence details |
| Ile 125 | Asn 125 | See sequence details |
| Tyr 132 | - | expression tag |
| Leu 133 | - | expression tag |
| His 134 | - | expression tag |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| Ala 137 | - | expression tag |
| His 138 | - | expression tag |
| His 139 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asn 89 | Lys 89 | See sequence details |
| Val 90 | Ile 90 | See sequence details |
| Ile 125 | Asn 125 | See sequence details |
| Ala 132 | - | expression tag |
| Ala 133 | - | expression tag |
| His 134 | - | expression tag |
| His 135 | - | expression tag |
| His 136 | - | expression tag |
| Ala 137 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Asn 89 | Lys 89 | See sequence details |
| Val 90 | Ile 90 | See sequence details |
| Ile 125 | Asn 125 | See sequence details |
| Tyr 132 | - | expression tag |
| Leu 133 | - | expression tag |
| His 134 | - | expression tag |
| Ala 135 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 61675.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 70.9 | |
| All* | Total formula weight | 61746.6 |
