6LKS

Effects of zinc ion on oligomerization and pH stability of influenza virus hemagglutinin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G, I... (K, A, C, E, G...)	Hemagglutinin HA1 chain	polymer	330	36662.1	6	UniProt (A7LI25)	Influenza A virus (A/Thailand/CU44/2006(H1N1))
2	B, D, F, H, J... (L, B, D, F, H...)	Hemagglutinin HA2 chain	polymer	183	20839.2	6	UniProt (A7LI25)	Influenza A virus (A/Thailand/CU44/2006(H1N1))
3	M, S, V (M, S, V)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1114.0	3	In PDB GlyTouCan (G61751GZ)
4	N, P (N, P)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		951.9	2	In PDB GlyTouCan (G10133VD)
5	O, Q, R, T, U... (O, Q, R, T, U...)	alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		748.7	6	In PDB GlyTouCan (G81315DD)
6	W (W)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
7	AA, CA, DA, EA, FA... (K, A, C, E, G...)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	19	Chemie (NAG)
8	BA, PA, TA (K, G, I)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
9	AB, BB, CB, DB, EB... (E, F, G, H, I...)	water	water		18.0	428	Chemie (HOH)

Sequence modifications

K, A, C, E, G, I: 1 - 326 (UniProt: A7LI25)

PDB	External Database	Details
Ala -3	-	expression tag
Asp -2	-	expression tag
Pro -1	-	expression tag
Gly 0	-	expression tag
Ile 116	Met 133	conflict

L, B, D, F, H, J: 1 - 176 (UniProt: A7LI25)

PDB	External Database	Details
Val 91	Ile 434	conflict
Ser 169	Asn 512	conflict
Ser 177	-	expression tag
Gly 178	-	expression tag
Arg 179	-	expression tag
Leu 180	-	expression tag
Val 181	-	expression tag
Pro 182	-	expression tag
Arg 183	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	345008.0
Branched	Number of molecules	12
	Total formula weight	10324.4
Non-Polymers*	Number of molecules	22
	Total formula weight	4399.2
All*	Total formula weight	359731.6

*Water molecules are not included.