6LDR
Structure of a K245A mutant of a Group II PLP dependent decarboxylase from Methanocaldococcus jannaschii, in complex with PLP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | L-tyrosine/L-aspartate decarboxylase | polymer | 415 | 47600.7 | 1 | UniProt (Q60358) Pfam (PF00282) | Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) | TDC/ADC |
| 2 | B (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | C (A) | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
| 4 | D, E (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | F (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | G (A) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A: 1 - 396 (UniProt: Q60358)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | expression tag |
| Gly -17 | - | expression tag |
| Ser -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Lys -14 | - | expression tag |
| Ile -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| His -9 | - | expression tag |
| His -8 | - | expression tag |
| His -7 | - | expression tag |
| Glu -6 | - | expression tag |
| Asn -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Tyr -3 | - | expression tag |
| Phe -2 | - | expression tag |
| Gln -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ala 245 | Lys 245 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47600.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 545.4 | |
| All* | Total formula weight | 48146.2 |
