6LD5
Zika NS5 polymerase domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RNA-directed RNA polymerase NS5 | polymer | 645 | 74904.2 | 1 | UniProt (A0A024B7W1) Pfam (PF00972) Pfam (PF20483) | Zika virus (isolate ZIKV/Human/French Polynesia/10087PF/2013) (ZIKV) | NS5 |
| 2 | B, C (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | 2,4-dimethoxy-5-thiophen-2-yl-benzoic acid | non-polymer | 264.3 | 1 | Chemie (G8O) | |||
| 4 | E (A) | quinoline-8-sulfonamide | non-polymer | 208.2 | 1 | Chemie (G8L) | |||
| 5 | F (A) | water | water | 18.0 | 652 | Chemie (HOH) |
Sequence modifications
A: 270 - 891 (UniProt: A0A024B7W1)
| PDB | External Database | Details |
|---|---|---|
| Met 247 | - | expression tag |
| His 248 | - | expression tag |
| His 249 | - | expression tag |
| His 250 | - | expression tag |
| His 251 | - | expression tag |
| His 252 | - | expression tag |
| His 253 | - | expression tag |
| Ser 254 | - | expression tag |
| Ser 255 | - | expression tag |
| Gly 256 | - | expression tag |
| Val 257 | - | expression tag |
| Asp 258 | - | expression tag |
| Leu 259 | - | expression tag |
| Gly 260 | - | expression tag |
| Thr 261 | - | expression tag |
| Glu 262 | - | expression tag |
| Asn 263 | - | expression tag |
| Leu 264 | - | expression tag |
| Tyr 265 | - | expression tag |
| Phe 266 | - | expression tag |
| Gln 267 | - | expression tag |
| Ser 268 | - | expression tag |
| Met 269 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 74904.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 603.4 | |
| All* | Total formula weight | 75507.5 |
