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6LCA

Crystal structure of human Dishevelled1 PDZ domain homotrimer

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E...Segment polarity protein dishevelled homolog DVL-1polymer10210771.18UniProt (O14640)
Pfam (PF00595)
In PDB
Homo sapiens (Human)Dishevelled-1,DSH homolog 1
2A, B, C, D, E...SULFATE IONnon-polymer96.18Chemie (SO4)
3waterwater18.022Chemie (HOH)
Sequence modifications
A, B, C, D, E, F, G, H: 246 - 340 (UniProt: O14640)
PDBExternal DatabaseDetails
Gly 239-expression tag
Pro 240-expression tag
Leu 241-expression tag
Gly 242-expression tag
Ser 243-expression tag
Asp 244-expression tag
His 245-expression tag
Ala 338Cys 338engineered mutation
Thr 339Trp 339engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight86168.4
Non-Polymers*Number of molecules8
Total formula weight768.5
All*Total formula weight86936.9
*Water molecules are not included.

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PDB entries from 2024-06-12

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