6LCA
Crystal structure of human Dishevelled1 PDZ domain homotrimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Segment polarity protein dishevelled homolog DVL-1 | polymer | 102 | 10771.1 | 8 | UniProt (O14640) Pfam (PF00595) | Homo sapiens (Human) | Dishevelled-1,DSH homolog 1 |
| 2 | I, J, K, L, M... (A, B, C, D, E...) | SULFATE ION | non-polymer | 96.1 | 8 | Chemie (SO4) | |||
| 3 | Q, R, S, T, U... (A, B, C, D, E...) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 246 - 340 (UniProt: O14640)
| PDB | External Database | Details |
|---|---|---|
| Gly 239 | - | expression tag |
| Pro 240 | - | expression tag |
| Leu 241 | - | expression tag |
| Gly 242 | - | expression tag |
| Ser 243 | - | expression tag |
| Asp 244 | - | expression tag |
| His 245 | - | expression tag |
| Ala 338 | Cys 338 | engineered mutation |
| Thr 339 | Trp 339 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 86168.4 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 768.5 | |
| All* | Total formula weight | 86936.9 |
