6LAZ
the wildtype SAM-VI riboswitch bound to a N-mustard SAM analog M1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA (55-MER) | polymer | 55 | 17896.5 | 2 | Bifidobacterium angulatum | ||
| 2 | C, D, E (C, D, E) | U1 small nuclear ribonucleoprotein A | polymer | 93 | 10796.7 | 3 | UniProt (P09012) Pfam (PF00076) | Homo sapiens (Human) | U1A |
| 3 | F (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | G, H (A, B) | (2~{S})-4-[[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl-(2-hydroxyethyl)amino]-2-azaniumyl-butanoate | non-polymer | 411.4 | 2 | Chemie (E7X) | |||
| 5 | I, J, K, L (A, C, D, E) | water | water | 18.0 | 18 | Chemie (HOH) |
Sequence modifications
C, D, E: 6 - 96 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 31 | Tyr 31 | engineered mutation |
| Arg 36 | Gln 36 | engineered mutation |
| Lys 46 | Ser 46 | engineered mutation |
| Met 97 | - | expression tag |
| Ala 98 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 68183.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 847.1 | |
| All* | Total formula weight | 69030.2 |
