6LAS
the wildtype SAM-VI riboswitch bound to SAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RNA (55-MER) | polymer | 55 | 17736.5 | 2 | Bifidobacterium angulatum | ||
| 2 | C, D, E (C, E, D) | U1 small nuclear ribonucleoprotein A | polymer | 93 | 10984.3 | 3 | UniProt (P09012) Pfam (PF00076) | Homo sapiens (Human) | U1A |
| 3 | F, G (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 4 | H, I, J, K, L (A, B, C, E, D) | water | water | 18.0 | 22 | Chemie (HOH) |
Sequence modifications
C, E, D: 6 - 96 (UniProt: P09012)
| PDB | External Database | Details |
|---|---|---|
| His 31 | Tyr 31 | engineered mutation |
| Arg 36 | Gln 36 | engineered mutation |
| Lys 46 | Ser 46 | engineered mutation |
| Mse 97 | - | expression tag |
| Ala 98 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 68425.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 796.9 | |
| All* | Total formula weight | 69222.8 |
