6L89
Human PPARgamma ligand binding domain complexed with Butyrolactone 1
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Peroxisome proliferator-activated receptor gamma | polymer | 287 | 32693.8 | 2 | UniProt (P37231) Pfam (PF00104) In PDB | Homo sapiens (Human) | PPAR-gamma,Nuclear receptor subfamily 1 group C member 3 |
2 | A, B | methyl (2R)-3-(4-hydroxyphenyl)-2-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methyl]-4-oxidanyl-5-oxidanylidene-furan-2-carboxylate | non-polymer | 424.4 | 2 | Chemie (E7C) | |||
3 | water | water | 18.0 | 143 | Chemie (HOH) |
Sequence modifications
A, B: 195 - 477 (UniProt: P37231)
PDB | External Database | Details |
---|---|---|
Gly 191 | - | expression tag |
Ser 192 | - | expression tag |
His 193 | - | expression tag |
Met 194 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 65387.6 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 848.9 | |
All* | Total formula weight | 66236.5 |