6L6K
Crystal structure of dimeric RXRalpha-LBD complexed with partial agonist CBt-PMN and SRC1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Retinoic acid receptor RXR-alpha | polymer | 243 | 27124.3 | 1 | UniProt (P19793) Pfam (PF00104) | Homo sapiens (Human) | Nuclear receptor subfamily 2 group B member 1,Retinoid X receptor alpha |
| 2 | B (B) | Nuclear receptor coactivator 1 | polymer | 12 | 1434.7 | 1 | UniProt (by SIFTS) (Q15788) | Homo sapiens | |
| 3 | C (A) | 1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)benzotriazole-5-carboxylic acid | non-polymer | 363.5 | 1 | Chemie (9HF) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 195 | Chemie (HOH) |
Sequence modifications
A: 224 - 462 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 220 | - | expression tag |
| Ser 221 | - | expression tag |
| Ser 222 | - | expression tag |
| His 223 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28559.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 403.5 | |
| All* | Total formula weight | 28962.5 |
