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6L5Z

Crystal strucutre of AF9 YEATS domain in complex with a cyclopeptide inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein AF-9polymer14116611.21UniProt (P42568)
Pfam (PF03366)
Homo sapiens (Human)ALL1-fused gene from chromosome 9 protein,Myeloid/lymphoid or mixed-lineage leukemia translocated to chromosome 3 protein,YEATS domain-containing protein 3
2B
(C)
SC0-ALO-ALA-SC3-SC4-NH2polymer6814.91synthetic constructCyclopeptide inhibitor
3C
(A)
waterwater18.04Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight17426.1
All*Total formula weight17426.1
*Water molecules are not included.

231029

PDB entries from 2025-02-05

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