6KZE
The crystal structue of PDE10A complexed with 4d
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | polymer | 322 | 37289.9 | 2 | UniProt (Q9Y233) | Homo sapiens (Human) | |
| 2 | C, F (A, B) | 8-[(E)-2-[5-methyl-1-[3-[3-(4-methylpiperazin-1-yl)propoxy]phenyl]benzimidazol-2-yl]ethenyl]quinoline | non-polymer | 517.7 | 2 | Chemie (DZU) | |||
| 3 | D, G (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | E, H (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 86 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 74579.9 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1214.8 | |
| All* | Total formula weight | 75794.6 |
