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6KZC

crystal structure of TRKc in complex with 3-(imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-N-(3-((4- methylpiperazin-1-yl)methyl)-5- (trifluoromethyl)phenyl)benzamide

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1ANT-3 growth factor receptorpolymer31235826.61UniProt (Q16288)
Pfam (PF07714)
In PDB
Homo sapiens (Human)GP145-TrkC,Trk-C,Neurotrophic tyrosine kinase receptor type 3,TrkC tyrosine kinase
2A3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-2-methyl-~{N}-[3-(4-methylpiperazin-1-yl)-5-(trifluoromethyl)phenyl]benzamidenon-polymer518.51Chemie (DZC)
3waterwater18.0205Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35826.6
Non-Polymers*Number of molecules1
Total formula weight518.5
All*Total formula weight36345.1
*Water molecules are not included.

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PDB entries from 2024-07-10

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