6KYP
X-ray structure of human PPARalpha ligand binding domain-GW9662-clofibric acid co-crystals obtained by delipidation and co-crystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Peroxisome proliferator-activated receptor alpha | polymer | 273 | 30856.1 | 2 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens | |
| 2 | C, D, E, F, G... (A, B) | 2-chloro-5-nitro-N-phenylbenzamide | non-polymer | 276.7 | 6 | Chemie (GW9) | |||
| 3 | I (B) | 2-(4-chloranylphenoxy)-2-methyl-propanoic acid | non-polymer | 214.6 | 1 | Chemie (E0O) |
Sequence modifications
A, B: 200 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 196 | - | expression tag |
| Ser 197 | - | expression tag |
| His 198 | - | expression tag |
| Met 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 61712.1 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1874.7 | |
| All* | Total formula weight | 63586.8 |
