6KXX
Human PPAR alpha ligand binding domain in complex with a synthetic agonist (compound A)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peroxisome proliferator-activated receptor alpha | polymer | 272 | 30684.8 | 1 | UniProt (Q07869) Pfam (PF00104) | Homo sapiens (Human) | PPAR-alpha,Nuclear receptor subfamily 1 group C member 1 |
| 2 | B (B) | PGC1alpha | polymer | 22 | 2405.8 | 1 | UniProt (by SIFTS) (Q9UBK2) | Homo sapiens | |
| 3 | C (A) | 1-(4-chlorophenyl)-6-methyl-3-propan-2-yl-pyrazolo[3,4-b]pyridine-4-carboxylic acid | non-polymer | 329.8 | 1 | Chemie (T02) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A: 200 - 468 (UniProt: Q07869)
| PDB | External Database | Details |
|---|---|---|
| Gly 197 | - | expression tag |
| Gly 198 | - | expression tag |
| Gln 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33090.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 329.8 | |
| All* | Total formula weight | 33420.4 |
